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Quinazoline compounds as sodium channel blockers
专利权人:
R. Richard Goehring;Jiangchao Yao;Laykea Tafesse
发明人:
R. Richard Goehring,Laykea Tafesse,Jiangchao Yao
申请号:
US13878004
公开号:
US09045435B2
申请日:
2011.10.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to aryl substituted quinazolines of Formula I, and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein G, A, and R1-R4 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
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