A method of processing physiological sensed signal is disclosed and includes: fetching a physiological sensed signal from a physiological detector, calculating signal aspects based on the sensed signal, adjusting a DC offset, and then adjusting signal intensity. The present invention dynamically adjusts operational parameters of the optical detector based on the signal aspects to adjust and improve detection quality and calculation preciseness for the physiological signal. In particular, the present invention can integrate more information and is applicable to a wearable device such that the user easily acquires physiological information. Further, the user is informed of the wearing state of the wearable device to achieve power saving.本發明係一種生理訊號量測處理方法，包括：讀取生理感測器的感測訊號，計算感測訊號的訊號特徵，調整感測訊號的基準偏移量，調整訊號強度。因此，本發明能根據訊號處理的生理訊號特徵，自動且動態地調整量測模組設定值，可提升生理訊號之量測品質與計算準確度。尤其是，很適合應用於穿戴式裝置，並具有整合多重資訊的特性，能讓使用者夠輕鬆地獲取生理資訊，進而調整生理訊號品質供後續生理訊號的計算及狀態判斷，並回報給使用者目前穿戴的狀態，還能根據這些狀態達而到省電功能。
