Bernhard Kaltenboeck,Ram B. Gupta,Erfan U. Chowdhury,Courtney A. Ober
申请号：
US14674711
公开号：
US20150297706A1
申请日:
2015.03.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are compositions, kits, and methods for inducing an immune response against an infection or a disease. The compositions typically include biodegradable particles having an average effective diameter of 0.5-20 μm, and optionally the compositions include one or more of an adjuvant, an apoptosis inhibitor, and an antigen. The compositions, kits, and methods may be utilized to induce a cell-mediated response, such as a T-helper cell response, and/or a humoral response against a pathogen or a disease. In some embodiments, the compositions, kits, and methods may be utilized to induce preferentially a Th1 response versus other types of immune responses such as a Th2 response.
