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Attenuated swine influenza vaccines and methods of making and use thereof
专利权人:
MERIAL INC.
发明人:
HAUSE BENJAMIN M.
申请号:
NZ70418813
公开号:
NZ704188A
申请日:
2013.07.11
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
An attenuated swine influenza strain capable of providing a safe and effective immune response in a porcine animal against a virulent H3N2 swine influenza or diseases caused by H3N2 swine influenza wherein the attenuated strain encodes an HA protein having five additional glycosylation sites, relative to its corresponding virulent parental strain wherein the virulent parental strain encodes an HA protein having the polypeptide sequence as set forth in SEQ ID NO: 18 and wherein the five glycosylation sites are S71N, K90N, L173T, P287T, and K294T.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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