COMPOSÉS DE MÉTALLOCÈNE ET MOLÉCULES MARQUÉES COMPRENANT CEUX-CI POUR L'IMAGERIE IN VIVO

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专利权人:

Aptenia S.R.L.

发明人:

申请号：

EP14711935.8

公开号：

EP2964661B1

申请日:

2014.03.05

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention concerns compounds and methods of labeling peptides or other molecules with 18 F or 19 F or any other suitable radionuclide of use, for example, in PET or NMR in vivo imaging. A targeting molecule such as a protein or a peptide is linked to a substituted metallocene complex which is reacted with the 18 F or 19 F shortly before performing the PET or NMR in vivo imaging on the patient. The labeled molecule is then used for targeting a cell, tissue, organ or pathogen to be imaged or detected.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/