WELCH, SIAO-KUN WAN,CALVERT, JAY GREGORY,SLADE, DAVID EWELL
申请号:
CA2817486
公开号:
CA2817486A1
申请日:
2011.11.09
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically- modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.