Jay Gregory Calvert,David Ewell Slade,Siao-Kun W. Welch
申请号:
US16809038
公开号:
US20200197507A1
申请日:
2020.03.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.