MELNICK, JOEL Z.,WHITE, JAY A.,PETKOVICH, P. MARTIN,TABASH, SAMIR P.,BISHOP, CHARLES W.,PEERS, SUSAN H.,STRUGNELL, STEPHEN A.
申请号:
CA2998426
公开号:
CA2998426A1
申请日:
2016.02.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Methods, compositions, and kits for adjunctive therapy using 25-hydroxyvitamin D are disclosed. The 25-hydroxyvitamin D may be administered with an agent that increases the risk of hypocalcemia, such as cinacalcet or a pharmaceutically acceptable salt thereof,and/or an anticancer agent. The adjunctive therapy is effective to treat and prevent iatrogenic hypocalcemia and/or secondary hyperparathyroidism, as well as delay cancer progression and the time to a post-treatment skeletal related event.