MELNICK, Joel Z.,WHITE, Jay A.,PETKOVICH, P. Martin,TABASH, Samir P,BISHOP, Charles W.,PEERS, Susan H.,STRUGNELL, Stephen A.
申请号:
PH12018500606
公开号:
PH12018500606A1
申请日:
2018.03.20
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
Methods, compositions, and kits for adjunctive therapy using 25-hydroxyvitamin D are disclosed. The 25-hydroxyvitamin D may be administered with an agent that increases the risk of hypocalcemia, such as cinacalcet or a pharmaceutically acceptable salt thereof,and/or an anticancer agent. The adjunctive therapy is effective to treat and prevent iatrogenic hypocalcemia and/or secondary hyperparathyroidism, as well as delay cancer progression and the time to a post-treatment skeletal related event.