A capsule guidance system includes a capsule including an imaging unit that captures an in-vivo image, a transmitting unit that transmits the image, and a magnetic field response unit a magnetic field generation unit that generates a magnetic field a receiving unit that receives the image a display unit that displays the image an operation input unit that inputs operation information for magnetically guiding the capsule a control unit that controls the magnetic field generation unit to guide the capsule in accordance with the operation information and a selection unit that selects at least two of a liquid surface, a submerged area, and a liquid bottom that is a lower boundary surface between the liquid and the outside as guidance areas into which the capsule medical device is guided. The control unit switches the magnetic field to be generated in accordance with the selected guidance area.