In a capsule medical device guidance system (1) according to the present invention, a magnetic-field-condition switching unit (46) switches a magnetic field a magnetic field generation unit (2) is caused to generate in accordance with the guidance area to which the capsule endoscope is guided and which is of one combination selected from among combinations that combine at least two of a liquid surface that is an upper boundary surface between a liquid inside the subject and the outside, a submerged area, and a liquid bottom that is a lower boundary surface between the liquid and the outside. A magnetic field control instruction unit (45) causes the magnetic field generation unit (2) to generate a magnetic field in conditions suitable for the switched guidance area.