The present disclosure generally relates to personalized nutritional compositions for pediatric subjects, wherein the nutritional composition can include one of three distinct profiles of human milk oligosaccharides (HMOs). The present disclosure also relates to methods for determining the composition of HMOs present in or that would be present in the breast milk of the mother of a pediatric subject as determined by the mother’s secretor status and/or Lewis blood group, and providing to the pediatric subject a nutritional composition comprising an HMO profile most similar to the HMOs present or that would be present in the breast milk of the subject’s mother.本揭露大致上關於用於兒童個體之個人化營養組成物，其中該營養組成物可包括三種不同人乳寡醣(HMO)輪廓分布(profile)之一者。本揭露亦關於用於判定存在於或由該母親的分泌者狀態(secretor status)和/或Lewis血型(路氏血型)來判定將會存在於兒童個體的母親之母乳中的HMO之組成物之方法，以及將包含最類似存在於或將會存在於該個體的母親的母乳中之HMO的HMO輪廓分布之營養組成物提供予該兒童個體之方法。
