Bitonti, Alan Joseph,Peters, Robert T,Mezo, Adam R,Rivera, Daniel S,Stattel, James M,Low, Susan C
申请号：
NO20055773
公开号：
NO339539B1
申请日:
2005.12.06
申请国别(地区):
NO
年份:
2016
代理人:
摘要：
A chimeric protein is synthesized by a) recombinantly expressing a fusion protein comprising at least a portion of an immunoglobulin constant region and a splicing protein capable of forming a C terminus thioester on the portion of an immunoglobulin constant region； b) adding a thiol cofactor to the fusion protein of a)； and c) adding at least one biologically active molecule having an N terminal cysteine.
