A mouthwash composition comprises water and a modified glutamic acid composed of a plurality of segment A and a plurality of segment B randomly arranged, in which, the segment A has the following formula I:The segment B has the following formula II:Wherein X=H, Na, K, NH4, 1/2Ca or 1/2Mg, and Y=Cl, Br, or I. The concentration of the modified glutamic acid in the mouthwash composition is 0.1~5 wt%. The mouthwash composition in the present invention can eliminate bad breath, and also has antibacterial properties, so it can suppress the formation of dental plaque and is effective in preventing periodontal disease.一種漱口水組成物,其組成包含水及一改質聚麩胺酸,改質聚麩胺酸係由複數個鏈段A及複數個鏈段B隨機排列所構成,鏈段A具有下列之化學式I:鏈段B具有下列之化學式II:其中,X為H、Na、K、NH4、1/2Ca或1/2Mg,Y為Cl、Br或I,且改質聚麩胺酸於該漱口水組成物中之濃度為0.1至5重量百分比。本發明所述之漱口水組成物除可治療口臭問題,其亦具有抗菌性,因此可以防止牙菌斑的生成,以及達到預防牙周病之效果。