PROCEDES D'UTILISATION D'UN ANTICORPS BISPECIFIQUE QUI RECONNAIT LE FACTEUR DE COAGULATION IX ET/OU LE FACTEUR DE COAGULATION IX ACTIVE ET LE FACTEUR DE COAGULATION X ET/OU LE FACTEUR DE COAGULATION X ACTIVE
F. HOFFMANN-LA ROCHE AG;CHUGAI SEIYAKU KABUSHIKI KAISHA
发明人:
YONEYAMA, KOICHIRO,SCHMITT, CHRISTOPHE
申请号：
CA3035327
公开号：
CA3035327A1
申请日:
2017.09.05
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
An objective of the present invention is to provide an effective pharmaceutical composition or a dosage regimen for preventing and/or treating bleeding, a disease accompanying bleeding, or a disease caused by bleeding. The inventors discovered that by administering a pharmaceutical composition comprising a bispecific antigen-binding molecule that recognizes (a) blood coagulation factor IX and/or activated blood coagulation factor IX and (b) blood coagulation factor X and/or activated blood coagulation factor X according to a given dosage regimen, bleeding, a disease accompanying bleeding, or a disease caused by bleeding can be prevented and/or treated more effectively.
