PROCÉDÉS D'UTILISATION D'UN ANTICORPS BISPÉCIFIQUE QUI RECONNAÎT LE FACTEUR DE COAGULATION IX ET/OU LE FACTEUR DE COAGULATION IX ACTIVÉ ET LE FACTEUR DE COAGULATION X ET/OU LE FACTEUR DE COAGULATION X ACTIVÉ
F. Hoffmann-La Roche AG;Chugai Seiyaku Kabushiki Kaisha
发明人:
YONEYAMA, Koichiro,SCHMITT, Christophe
申请号：
EP17848753
公开号：
EP3509637A4
申请日:
2017.09.05
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
An objective of the present invention is to provide an effective pharmaceutical composition or a dosage regimen for preventing and/or treating bleeding, a disease accompanying bleeding, or a disease caused by bleeding. The inventors discovered that by administering a pharmaceutical composition comprising a bispecific antigen-binding molecule that recognizes (a) blood coagulation factor IX and/or activated blood coagulation factor IX and (b) blood coagulation factor X and/or activated blood coagulation factor X according to a given dosage regimen, bleeding, a disease accompanying bleeding, or a disease caused by bleeding can be prevented and/or treated more effectively.
