Benzoxazole derivatives having inhibitory activity against interleukin-6, preparation method thereof, and pharmaceutical composition containing the same
Jung Ho Choi;Hea Young Park Choo;Young Kook Kim;Jin Ah Kim
发明人:
Hea Young Park Choo,Young Kook Kim,Jung Ho Choi,Jin Ah Kim
申请号:
US13805136
公开号:
US08614240B2
申请日:
2011.06.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to benzoxazole derivatives represented by the Formula 1, which has an inhibitory activity against interleukin-6 (IL-6), a method for preparation thereof, and a pharmaceutical composition containing the same. The compound represented by the Formula 1 according to the present invention has a superior inhibitory activity against interleukin-6, and therefore, can be practically applied for prevention and treatment of diseases caused by abnormal interleukin-6 activity.