KYM, PHILIP R.,WANG, XUEQING,SEARLE, XENIA B.,LIU, BO,YEUNG, MING C.
申请号：
CA2966023
公开号：
CA2966023A1
申请日:
2015.10.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Compounds of formula (I) and pharmaceutically acceptable salts or radiolabeled forms thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and m are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
