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TARGETED SUSTAINED-RELEASE MICROSPHERE OF VASCULAR OCCLUSIVE AGENT CONTAINING SODIUM ALGINATE AND SORAFENIB, PRODUCTION METHOD AND USE THEREOF
专利权人:
BEIJING SHENGYIYAO SCIENCE & TECHNOLOGY DEVELOPMENT CO.; LTD
发明人:
LI, XINJIAN,HONG, HONG,LU, GE
申请号:
EP10764096
公开号:
EP2420227A4
申请日:
2010.04.14
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A targeted sustained-release microsphere vascular embolizing agent, the production method and the use thereof are disclosed. The microsphere comprises sodium alginate as the carrier and sorafenib as the targeted anti-tumor medicine and sorafenib is encapsulated by sodium alginate. The weight ratio of sorafenib to sodium alginate is 1:1ˆ¼1:30. The microspheres are used for manufacturing medicament for the treatment of solid tumors with advantages induing high medicine concentration in the target regions with reduced systemic dosage and toxic and side effects.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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