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TARGETED SUSTAINED-RELEASE MICROSPHERE OF VASCULAR OCCLUSIVE AGENT CONTAINING SODIUM ALGINATE AND SORAFENIB, PRODUCTION METHOD AND USE THEREOF
专利权人:
BEIJING SHENGYIYAO SCIENCE & TECHNOLOGY DEVELOPMENT CO.; LTD
发明人:
LI, XINJIAN,HONG, HONG,LU, GE
申请号:
CA2758820
公开号:
CA2758820C
申请日:
2010.04.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
A targeted sustained-release microsphere vascular embolizing agent, theproduction method and the use thereof are disclosed. The microsphere comprisessodium alginate as the carrier and sorafenib as the targeted anti-tumormedicineand sorafenib is encapsulated by sodium alginate. The weight ratio ofsorafenib tosodium alginate is 1:1-1:30. The microspheres are used for manufacturingmedicament for the treatment of solid tumors with advantages including highmedicine concentration in the target regions with reduced systemic dosage andtoxic and side effects.
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