MARUTHACHALAM, BHARATHIKUMAR VELLALORE,LIU, JIANGHAI,MOHAMMAD, AYMAN ELSAYED,FONGE, HUMPHREY,BARRETO, KRIS,GEYER, CLARENCE RONALD
申请号:
CA3072267
公开号:
CA3072267A1
申请日:
2018.08.09
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The disclosure is directed to antibodies and binding fragments thereof that specifically bind HER3. The disclosure is further directed to immunoconjugates comprising the antibodies and binding fragments thereof that specifically bind HER3. The disclosure is also directed to uses of the antibodies, binding fragments thereof and immunoconjugates for detecting HER3-expressing cells and for treating HER3- expressing cancer.