BRADBURY, BARTON JAMES,DESHPANDE, MILIND,HASHIMOTO, AKIHIRO,KIM, HA YOUNG,LUCIEN, EDLAINE,PAIS, GODWIN,PUCCI, MICHAEL,WANG, QIUPING,WILES, JASON ALLAN,PHADKE, AVINASH
申请号：
NZ59544810
公开号：
NZ595448A
申请日:
2010.04.05
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
Disclosed herein are hydroxythienoquinolones and related compounds and their pharmaceutically acceptable salts useful as antiviral agents and having the general formula (I) in which the variables R2, R6, and R7 are defined herein. Certain compounds provided herein possess potent antibacterial, antiprotozoal, or antifungal activity and are particularly efficacious for the treatment of MRSA infections. The disclosure also provides pharmaceutical compositions, pharmaceutical compositions containing a hydroxythienoquinolone in combination with one or more other active agent, and methods of treating microbial infections in animals by administering an effective amount of a hydroxythienoquinolone or related compound to an animal suffering from a microbial infection.
