Barton James Bradbury;Ha Young Kim;Michael Pucci;Jason Allan Wiles;Qiuping Wang;Edlaine Lucien;Avinash Phadke;Milind Deshpande;Akihiro Hashimoto;Godwin Pais
发明人:
Barton James Bradbury,Milind Deshpande,Akihiro Hashimoto,Ha Young Kim,Edlaine Lucien,Godwin Pais,Michael Pucci,Qiuping Wang,Jason Allan Wiles,Avinash Phadke
申请号：
US12754057
公开号：
US08173636B2
申请日:
2010.04.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are hydroxylthienoquinolones and related compounds and their pharmaceutically acceptable salts useful as antiviral agents and having the general formulain which the variables R2, R6, and R7 are defined herein. Certain compounds provided herein possess potent antibacterial, antiprotozoal, or antifungal activity and are particularly efficacious for the treatment of MRSA infections. The invention also provides pharmaceutical compositions, pharmaceutical compositions containing a hydroxylthienoquinolone in combination with one or more other active agent, and methods of treating microbial infections in animals by administering an effective amount of a hydroxylthienoquinolone or related compound to an animal suffering from a microbial infection.
