DELLINGER RYAN,MIGAUD MARIE EUGENIE,REDPATH PHILIP,RHONEMUS TROY,CUNNINGHAM RICHARD
申请号：
IN201717035622
公开号：
IN201717035622A
申请日:
2017.10.07
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
Derivatives of nicotinic acid riboside (NAR) nicotinamide riboside (NR) and reduced NAR and NR including 1 (2 3 5 triacetyl beta D ribofuranosyl) 1 4 dihydronicotinic acid (4a) and compositions containing the same and/or reduced derivative forms of nicotinamide riboside including 1 (2 3 5 triacetyl beta D ribofuranosyl) 1 4 nicotinamide (2) are provided for use in the care of treatment of skin and skin conditions. In some embodiments the invention relates to pharmaceutical compositions and cosmetic compositions containing one or more NR NAR NRH or NARH derivatives or prodrugs or salts thereof. In further embodiments the invention relates to methods of using one or more NR NAR NRH or NARH derivatives or prodrugs solvates or salts thereof to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival and overall cell and tissue health.
