Devices and methods for ameliorating hypothermia or risk of occurrence thereof in non-human mammals are provided. Embodiments of the subject devices include a limb enclosure unit and a liquid flow path associated with the enclosure unit. In some versions, the liquid flow path is configured to bring a warm liquid in heat transfer relationship with a limb of a small non-human mammal present in the enclosure unit. Methods for using such devices are also provided and in some versions include moving a warm liquid through the flow path in a manner sufficient to ameliorate hypothermia or the risk of occurrence thereof in the small non-human mammal.