ANDERSON, DAVID RANDOLPH,BUNNAGE, MARK EDWARD,CURRAN, KEVIN JOSEPH,DEHNHARDT, CHRISTOPH MARTIN,GAVRIN, LORI KRIM,GOLDBERG, JOEL ADAM,HAN, SEUNGIL,HEPWORTH, DAVID,HUANG, HORNG-CHIH,LEE, ARTHUR,LEE, KAT
申请号:
SG11201608110W
公开号:
SG11201608110WA
申请日:
2015.03.26
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula,as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment of autoimmune and inflammatory diseases associated with Interleukin-1 Receptor Associated Kinase (IRAK), methods of synthesis, and intermediates are also disclosed.