ANDERSON DAVID RANDOLPH,BUNNAGE MARK EDWARD,CURRAN KEVIN JOSEPH,DEHNHARDT CHRISTOPH MARTIN,GAVRIN LORI KRIM,GOLDBERG JOEL ADAM,HAN SEUNGIL,HEPWORTH DAVID,HUANG HORNG-CHIH,LEE ARTHUR,LEE KATHERINE LIN
申请号:
AP2016009514
公开号:
AP2016009514A0
申请日:
2015.03.26
申请国别(地区):
AP
年份:
2016
代理人:
摘要:
Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula,as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment of autoimmune and inflammatory diseases associated with Interleukin-1 Receptor Associated Kinase (IRAK), methods of synthesis, and intermediates are also disclosed.