JOHNSON, KEITH,LATHROP, ROBERT,YANG, MEIDONG,MAULHARDT, HOLLY,FRANKE, ROLAND
申请号:
CA2998483
公开号:
CA2998483A1
申请日:
2016.09.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.