Keith JOHNSON,Robert LATHROP,Meidong YANG,Holly MAULHARDT,Roland FRANKE
申请号:
US15899228
公开号:
US20180177739A1
申请日:
2018.02.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are compositions and methods useful for enhancing the skin penetration of drug nanoparticles. The compositions can be hydrophobic and include a hydrophobic carrier, a volatile silicone fluid, and drug nanoparticles. Also disclosed are methods for inhibiting crystal growth of drug nanoparticles in an aqueous carrier or a hydrophobic carrier. Further, methods to topically treat psoriasis using compositions containing nanoparticles of paclitaxel or other taxanes are disclosed.