1,4 oxazines as BACE1 and/or BACE2 inhibitors

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专利权人:

Emanuele Gabellieri;Robert Narquizian;Massimiliano Travagli;Wolfgang Wostl;Matteo Andreini

发明人:

Matteo Andreini,Emanuele Gabellieri,Robert Narquizian,Massimiliano Travagli,Wolfgang Wostl

申请号：

US13357640

公开号：

US08399459B2

申请日:

2012.01.25

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention provides 1,4 Oxazines of formula Ihaving BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.

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