A syringe is provided. The syringe (10) comprises a barrel (11) with a lumen, said barrel (11) being adapted to contain a drug, the barrel (11) having a distal end wall portion (13) and a tubular wall (12) extending proximally from said distal end wall portion (13). The barrel (11) extending along an axis (100), whereby the distal end wall portion (13) has an opening (14) extending into a syringe head (40) adapted to receive a syringe needle, said syringe head (40) having a lumen smaller in transversal crosssection than the barrel lumen. The syringe (10) further comprises a plunger shaft (96) extending along the axis (100), said plunger shaft being displaceable along the axis (100) within said barrel (11) and a plunger (30) attached to a distal end of said plunger shaft (96)； the plunger (30) being adapted to be in fluid-tight engagement with the tubular wall (12) of the barrel (11). The plunger (30) further has a protrusion (33) adapted to fit in fluid-tight engagement in the lumen of the syringe head (40). The syringe head (40) comprising at least one axial passage (42) in fluid communication with the barrel (11), said axial passage (42) being located laterally of the protrusion (33) when the protrusion (33) is positioned in the lumen of the syringe head (40).
