Yissum Research Development Company of the Hebrew University of Jerusalem Ltd;The Medical Research, Infrastructure, and Health Services Fund of the Tel Aviv Medical Center
发明人:
Gertler, Arieh,Elinav, Eran,Halpern, Zamir
申请号：
AU2011243965
公开号：
AU2011243965A1
申请日:
2011.04.17
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Leptin muteins, in particular leptin antagonists, with increased binding affinity to leptin receptor are provided. These compounds as well as pharmaceutical composition comprising them are useful for the treatment of any disorder in which a non-desirable or deleterious activity of endogenous leptin or an altered innate immune response is implicated.
