John Anderson,Jonathan Fisher,Martin Pulé,Kenth Gustafsson
申请号:
US15567165
公开号:
US20180125890A1
申请日:
2016.04.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a T cell which expresses a gamma-delta T cell receptor (TCR) and a chimeric antigen receptor (CAR), wherein the CAR comprises: an antigen binding domain; a transmembrane domain; and a co-stimulatory intracellular signalling domain; wherein the intracellular signalling domain provides a co-stimulatory signal to the T cell following binding of antigen to the antigen binding domain.