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TROPISM-MODIFIED RECOMBINANT VIRAL VECTORS AND USES THEREOF FOR THE TARGETED INTRODUCTION OF GENETIC MATERIAL INTO HUMAN CELLS
专利权人:
INC.;REGENERON PHARMACEUTICALS
发明人:
KYRATSOUS, Christos,MURPHY, Andrew J.,WANG, Cheng,SABIN, Leah
申请号:
SG11201911610T
公开号:
SG11201911610TA
申请日:
2018.06.27
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
Provided herein are compositions and methods for retargeting recombinant viral capsid proteins/capsids/vectors, e.g., in vivo, with a multispecific binding molecule, such as a bispecific antibody, that specifically binds a heterologous epitope displayed by the capsid protein and a protein expressed on the cell of interest for the targeted delivery of a nucleotide of interest.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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