Li Zhong,Sergei Zolotukhin,Lakshmanan Govindasamy,Mavis Agbandje-McKenna,Arun Srivastava
申请号：
US13855640
公开号：
US09157098B2
申请日:
2013.04.02
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors.
