JEFFERIES, WILFRED,BASHA, GENC,OMILUSIK, KYLA,CHAVEZ-STEENBOCK, ANA
申请号：
HK15104521.3
公开号：
HK1203979A
申请日:
2015.05.13
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
Compositions for and methods of stimulating a MHC I mediated immune response comprising stimulating MHC I endolysosomal cross presentation in dendritic cells. Stimulation MHC I endolysosomal cross presentation may comprise over-expression CD74 in dendritic cells and/or targeting antigens to the MHC I endolysosomal cross presentation pathway. Fusion proteins comprising an antigen or fragment thereof and a CD74 endolysosomal targeting sequence are also provided.
