The present application relates to novel, chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to a method for their preparation, to their use on their own or in combinations for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diseases of the respiratory tracts, the lung and the cardiovascular system.本申請案係關於新穎的掌性2,5-二取代環戊烷羧酸衍生物、其製備方法、其本身用途或結合用於治療及/或預防疾病,及關於其用於製造治療及/或預防疾病的藥劑之用途,特別係治療及/或預防呼吸道、肺和心血管系統疾病。