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Lipopeptides for delivery of nucleic acids
专利权人:
Marina Biotech; Inc.
发明人:
Roger C. Adami,Michael E. Houston, Jr.,Rachel E. Johns
申请号:
US14941910
公开号:
US09821067B2
申请日:
2015.11.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Lipopeptide compounds having a central peptide HHHHHKHHHKKKHKHKKK (SEQ ID NO:15) and a lipophilic group attached to each terminus of the peptide, and salts thereof. The lipopeptides are useful for forming pharmaceutical compositions for delivery of nucleic acid agents, such as siRNA and mdRNA agents, as well as in methods for treating the signs and symptoms of disease.
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