THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人:
WYSS-CORAY, ANTON,CASTELLANO, JOSEPH M.
申请号:
CA2989138
公开号:
CA2989138A1
申请日:
2016.06.06
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.