In an arrangement and method for active vibration compensation of an x-ray radiator, a counter-vibration generation unit is arranged within the x-ray radiator to reduce a vibration arising during operation of the x-ray radiator. The counter-vibration generating unit is engaged in an active connection with the x-ray radiator and generates a counter-vibration that is phase-shifted by 180 degrees relative to the operational vibration. Operational vibrations generated by the x-ray radiator can be directly reduced at the point of origin by the application of active counter-vibrations in the immediate proximity of the vibration generator. Additional vibration transmission to other system parts (for example a C-arm) is thereby reduced or prevented.