RABINOVICH, Gabriel Adrian,RUSSO, Diego Omar Croci,CERLIANI, Juan Pablo,SALATINO, Mariana
申请号:
EP14865112
公开号:
EP3074037A4
申请日:
2014.11.26
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
A method for modulating angiogenesis in a cancer or tumor refractory to anti-VEGF, including identifying a cancer cell as being referactory to anti-VEGF, and then contacting the cancer cell refractory to anti-VEGF with an effective amount of an agent that modulates interaction between Gal1 or a Gal1 fragment and the natural binding partner of Gal1 or the Gal1 fragment to thereby modulate angiogenesis.