INIS BIOTECH LLC;CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS;FUNDACIÓN SALES
发明人:
Gabriel Adrian Rabinovich,Diego Omar Croci Russo,Juan Pablo Cerliani,Mariana Salatino,Pablo Francisco Hockl,Juan Manuel Pérez Sáez
申请号：
US16416996
公开号：
US20200016266A1
申请日:
2019.05.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method for modulating angiogenesis in a cancer or tumor refractory to anti-VEGF, including identifying a cancer cell as being referactory to anti-VEGF, and then contacting the cancer cell refractory to anti-VEGF with an effective amount of an agent that modulates interaction between Gal1 or a Gal1 fragment and the natural binding partner of Gal1 or the Gal1 fragment to thereby modulate angiogenesis.
