(I) a quaternary ammonium neuromuscular blocker； And (ii) an excipient selected from a polyhydroxy acid of the formula (1), an intramolecular lactone of such a polyhydroxy acid or a mixture thereof. [Chemical Formula 1] HO-CH 2 - [CH ( OH)] n -COOH In the above formula, n is an integer of 1 to 8. The present invention also relates to a liquid pharmaceutical composition comprising or consisting of said aqueous composition； And (a) providing a quaternary ammonium neuromuscular blocker that is optionally lyophilized； (b) providing an excipient that is optionally freeze-dried, selected from a polyhydroxy acid of the formula (1), an intramolecular lactone of such a polyhydroxy acid or a mixture thereof； And (c) mixing the quaternary ammonium nerve root blocker of step (a) and the excipient of step (b) in water to provide an aqueous composition <； RTI ID = 0.0 >； and / or <； / RTI >； [Chemical Formula 1] HO-CH 2 - [CH ( OH)] n -COOH In the above formula, n is an integer of 1 to 8. The present invention also relates to the use of a polyhydroxycarboxylic acid of the formula 1, an intramolecular lactone of such a polyhydroxy acid or a mixture thereof for stabilizing an aqueous composition comprising a quaternary ammonium nerve root blocker: [Chemical Formula 1] HO-CH 2 - [CH ( OH)] n -COOH In the above formula, n is an integer of 1 to 8. The invention also relates to a container comprising an aqueous or liquid pharmaceutical composition of the invention. The present invention also relates to a kit comprising the composition. Preferred embodiments are expressly set forth in the dependent claims.본 발명은 (ⅰ) 4차 암모늄 신경근 차단제； 및 (ⅱ) 하기 화학식 1의 폴리하이드록시산, 이러한 폴리하이드록시산의 분자 내 락톤 또는 이들의 혼합물로부터 선택된 부형제를 포함하는, 수성 조성물에 관한 것이다: [화학식 1] HO-CH2-[CH(OH)]n-COOH상기 식에서, n은 1 내지 8의 정수이다. 또한, 본 발명은 상기 수성 조성물을 포함하거나 상기 수성 조성물로 구성된 액체 약학 조성물； 및 (a) 선택적으로 동결건조될 수 있는, 4차 암모늄 신경근 차단제를 제공하는 단계； (b) 하기 화학식 1의 폴리하이드록시산, 이러한 폴리하이드록시산의 분자 내 락톤 또는 이들의 혼합물로부터 선택된, 선택적으로 동결건조될 수 있는, 부형제를 제공하는
