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Stabilized aqueous composition of neuromuscular blocking agents
专利权人:
メルズンゲン;ビー.ブラウン;ビー.ブラウン メルズンゲン アーゲー;アーゲー
发明人:
ジル ベジャー,ファン,ティモネーダ ラミア,クリスティーナ,ジル ベジャー,ファン,ティモネーダ ラミア,クリスティーナ
申请号:
JP2015533539
公开号:
JP6347784B2
申请日:
2013.09.19
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
The invention relates to an aqueous composition comprising a quaternary ammonium blocking agent and a polyhydroxy acid based excipient, and a method for producing said composition. In particular the neuromuscular blocking agent may be a Rocuronium salt and the excipient is an aldonic acid, e. g. gluconic acid or an intramolecular lactone thereof. Furthermore, the invention relates to a liquid pharmaceutical composition comprising said aqueous composition. The compositions of the present invention can further be comprised in a container made of glass or an organic polymer. Additionally, the invention relates to a pharmaceutical kit comprising the compositions of the present invention.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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