METHODS FOR IDENTIFYING MODULATORS OF IL-24 MEDIATED APOPTOSIS AND IMMUNOTHERAPY

• 收藏
• 分享

专利权人:

发明人:

Moira Sauane,Winchie Do

申请号：

US14476259

公开号：

US20150064239A1

申请日:

2014.09.03

申请国别(地区):

US

年份:

2015

代理人:

摘要：

A method for identifying modulators of Interleukin 24 (IL-24) mediated apoptosis is disclosed. For IL-24 apoptosis to be effective, the cells should express Sigma 1 Receptor (S1R). Additionally apoptosis modulators can be identified by exposing biological cells to test compounds and monitoring for signs of endoplasmic reticulum (ER) stress protein expression calcium mobilization or reactive oxygen species (ROS) production.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/