David GILHAM,Eytan BREMAN,Benjamin DEMOULIN,Simon BORNSCHEIN,Susanna RAITANO
申请号：
US16769627
公开号：
US20200318067A1
申请日:
2018.12.05
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present application relates to the field of immunotherapy, more particularly to the manufacture of cells for adoptive cell therapy. Provided herein are methods to prevent and/or reduce fratricide during manufacturing of such cells, particularly of cells expressing a chimeric NKG2D receptor. Also provided are cells and compositions comprising cells in which fratricide is prevented and/or reduced.
