KIM, JONG HOON,김종훈,HAN, JI YOU,한지유,JANG, YU JIN,장유진
申请号：
KR1020150114352
公开号：
KR1020170019883A
申请日:
2015.08.13
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a production method of high-function hepatocyte, which differentiates into hepatocyte from human pluripotent stem cells, and increases the expression and activity of drug metabolizing enzyme and the physiological function of the hepatocyte by repetitively treating xenobiotics on the differentiated hepatocyte.본 발명은 인간 만능 줄기세포로부터 간세포로 분화한 후, 분화된 간세포에 생체이물(xenobiotics)을 반복 처리하여 약물대사효소의 발현 및 활성과 간세포의 생리학적 기능을 높이는 고기능성 간세포의 제조방법에 관한 것이다.
