LIU ZHENTAO,YANG HANYU,GAO YUQING,SHEN DONGMIN,GUO WENMIN,FENG XIAOLONG,ZHENG JIA,YANG LIYING
申请号:
IN1030/KOLNP/2007
公开号:
IN254307B
申请日:
2007.03.23
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention relates to a novel drug delivery and release system, i.e. Self- emulsifying Drug Delievery System (SEDDS), of butylphthalide, to a preparation process thereof, and to a use thereof in a pharmaceutical formulation. The drug delivery system comprises as essential ingredients 1% to 65% of butylphthalide and 10% to 65% of a emulsifying agent, together with various excipients as required depending on the desired dosage forms. The present invention significantly increases the contact area between butylphthalide and the mucous membrane of the gastrointestinal tract, and therefore improves the absorptivity of the drug.