Connor, Eric,Biyani, Kalpesh,Cope, Michael J.,Liu, Futian,Charmot, Dominique,Mansky, Paul,Mong, Tony Kwok-Kong,Liu, Mingjun,Chen, Yan,Chang, Han-Ting
申请号：
AU2006299449
公开号：
AU2006299449B2
申请日:
2006.10.02
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention provides methods and compositions for the treatment of ionimbalances using core-shell composites and compositions comprising such core-shellcomposites. In particular, the invention provides core-shell particles andcompositions comprising potassium binding polymers, and core-shell particles andcompositions comprising sodium binding polymers, and in each case, pharmaceutical compositionsthereof. Methods of use of the polymeric and pharmaceutical compositions fortherapeutic and/or prophylactic benefits are also disclosed. The compositions andmethods of the invention offer improved approaches for treatment of hyperkalemia andother indications related to potassium ion homeostasis, and for treatment ofhypertension and other indicates related to sodium ion homeostasis.
