Active ingredient, additives body is pharmaceutically acceptable, and supercritical fluids present invention, - a step of making tablets by tableting the mixture containing the soluble substances, supercritical contacting a supercritical fluid the tablet The method for producing the same and oral rapidly disintegrating tablet was manufactured by a method comprising the steps of extracting soluble material, to form micropores in the tablet - the fluid. [Selection] Figure Figure 1本発明は、活性成分、薬学的に許容可能な添加体、及び超臨界流体-可溶性物質を含む混合物を打錠して錠剤を製造する段階と、前記錠剤を超臨界流体と接触させて超臨界流体-可溶性物質を抽出し、錠剤中に微細空隙を形成させる段階とを含む方法によって製造された口腔内速崩壊錠及びその製造方法を提供する。【選択図】図1
